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A., Roca, C

Each peptide pair below shares a general category, yet the two members differ enough in receptor selectivity, half-life, and adverse-effect profile that swapping one for the other changes both outcomes and risk

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From experimental data of kinetic measurements of BRET, following vehicle and baseline corrections, quantification of induced responses from individual peptide concentrations was determined by calculating the net area under curve from the 10 min response (AUC 0-10min) ) in GraphPad Prism version 9.0.1 (GraphPad Software Inc., San Diego, CA)