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Dosage should be reviewed regularly, especially during the first few months of treatment or when side effects occur

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The presence of small air bubbles in GLP-1 injection pens is not dangerous and poses minimal risk to patients when the medication is administered subcutaneously (under the skin) as intended

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[9] Patients should be advised to contact their healthcare provider if they experience any severe or persistent side effects, such as difficulty breathing, chest tightness, severe rash, or dizziness

However, this method suffers from a disadvantage associated with a difficulty of application thereof to a practical process due to a high cost of (S)-3-hydroxy-gamma-butyrolactone as the starting material