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However, even the most specific inhibitor can have effects beyond the therapeutic target, i.e., off-target effects, which may significantly affect the outcome

Clin Hematol 4:83, 1975

During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]

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All authors were involved in the drafting, critical review, revision, and final approval of the manuscript