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H., Assadi, A

1-12, Mansour, Meghan R., et al

doi: 10.1007/s11892-020-1284-5 46 QianYXiaFZuoYZhongMYangLJiangYet al

Acetyl-CoA is also an allosteric activator of pyruvate carboxylase that catalyzes the gluconeogenesis pathway which is active during catabolic states such as fasting.[6][15][16] In carnitine deficient states, LCFAs cannot be effectively transported to the mitochondria matrix for oxidation and subsequent utilization in Krebs cycle and ketone body production