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GHK-Cu, a copper-containing tripeptide naturally present in human serum, has been investigated for its potential role in collagen remodeling and tissue regeneration

Ann Neurol 1989;26:456

In one single-center trial of 72 subjects using a controlled-adverse-environment model, the T4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported

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Hormonal influences on metabolism and fat distribution are notable during perimenopause