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Like the other common effects, this one tends to fade as the body adjusts to the therapy

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In addition, sorafenib, a kinase inhibitor approved for the treatment of RCC and HCC, inhibits SLC7A11 to suppress the growth of these tumors via the induction of ferroptosis 67,68

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) Specifically, the changes to the gut microbiome composition caused a reduction in the intestinal cells that produce mucin, which is the barrier that prevents microbes from causing inflammation in the gut

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