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Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle

This is the system that controls involuntary actions like heart rate and blood pressure

Furthermore, a dedicated CV mode of action trial with semaglutide in subjects with type 2 diabetes and CV disease is also ongoing, which includes inflammation in atherosclerosis as the primary endpoint (NCT04032197)

For references and more information , see the section on Age-related cognitive decline in the in-depth article on Cognitive Function

There are multiple classes of diabetes medications available, and your doctor can advise whether other options might be more suitable given your IBD

doi: 10.1016/j.envint.2017.12.033