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Open Biol 10:200004 Yang B-B, Lum PK, Hayashi MM, Roskos LK (2004) Polyethylene glycol modification of filgrastim results in decreased renal clearance of the protein in rats

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Inject slowly, remove the needle, and apply light pressure with a cotton ball or gauze

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There have been negative effects observed as well, suggesting that DPI (and other related structures) act as pro-oxidants by decreasing GSH (Riganti et al., 2004)

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