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Expert Opinion on Pharmacotherapy, 17 (11), 1561

Keywords: antidiabetic drug, cross-sectional survey, discontinuation, incretins, incretin therapy, glycemic control Introduction Diabetes is a highly prevalent condition, affecting 8.5% of the global population, requiring early diagnosis and treatment to increase the likelihood of favorable outcomes

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Under continuous stimulation of IGF-1, IGF-1R/MAPK/PI3K signaling is activated, leading to resistance to estrogen tamoxifen and fluvestrant