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For Canadians seeking significant body composition changes, Retatrutide represents the most promising peptide currently in late-stage development, with protein intake of 80-100g daily being essential for optimal muscle preservation during treatment

12 Similar results were seen in another study which investigated the impact of BCAA supplementation in wrestlers in a calorie deficit

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The 15 nmol/kg dose modestly reduced glucose and HbA1c but failed to induce normoglycemia (defined as blood glucose 10%)