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The authors have investigated three treatments to correct metabolic abnormalities which have demonstrated improvement in behavior and/or metabolism, namely the combination of methylcobalamin (mB12) with low-dose folinic acid (LDFA) to treat oxidative stress in an open-label study (James et al., 1A demonstrates where these agents are believed to act within four major interconnected metabolic pathways that are known to be disrupted in ASD

This activity is primarily concentrated in the United States, China, and South Korea, and reflects diverse therapeutic directions in gynecological and endocrine disorders (Table 3)

Int J Pharm Investig 2:12