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While analyses restricted to participants with established cardiovascular disease yielded MACE results that were directionally consistent with the overall analysis, conclusions are limited because subgroup estimates were based on trial-level reporting rather than individual participant data, and included studies continued to differ in patient characteristics, definitions of established cardiovascular disease, background therapies, and trial era

Analogously, polymers without polyfluorinated moieties, followingly referred to as P1 and the ruthenium catalyst derivative P2 were prepared (Supplementary Fig

1D) showed that PLB significantly down-regulated cytochrome C and Ferritin, while up-regulating TFAM and GPX4, suggesting that PLB promotes the survival and functional recovery of ovarian cells by regulating apoptosis and ferroptosis-related pathways

ParkerBAWaltonCMCarrSTAndrusJLCheungEDupliseaMJet al

10.1007/BF01958877 16

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