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GP100095: RPB1 CTD(1615-1621-Lys)-Tn(1619) Pack Size:2 mg the intracellular monosaccharide modification central

SKU: 62859700980

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Description

the intracellular monosaccharide modification central to O-GlcNAcylation signaling

N‐Benzyloxycarbonyloxy-6-aminohexyl 2-acetamido-3

The terminal amine is protected with a benzyloxycarbonyl (Cbz) group

Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Ser) at Ser140

C17H30O13 / 442

GP100095: RPB1 CTD(1615-1621-Lys)-Tn(1619) Pack Size:2 mg the intracellular monosaccharide modification centralC46H73N11O18 1068. 1 DNA directed RNA polymerase II (Pol II) subunit RPB1 contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr Ser Pro Thr Ser Pro Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process

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