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The review also confirmed GLP-1s cardioprotective and neuroprotective effects, its ability to decrease inflammation and apoptosis, and its roles in learning and memory, reward behaviour, and food palatability via central GLP-1R-expressing circuits
[33] Columbia University
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[12] [13] Rare but serious class effects: GLP-1-based therapies are associated with rare but serious adverse effects, including pancreatitis and gallbladder disease, as noted in the SmPCs for licensed agents in this class
Safety Profile: Mild to moderate gastrointestinal side effects (e.g., nausea, vomiting, diarrhea, constipation) were most common, primarily during dose escalation
