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The challenge is not whether GHK-Cu has biological activity (that is well-established) but whether that activity can be delivered to tissues at concentrations and durations sufficient to produce clinical effects beyond the skin surface

For the purpose of getting a reliable and science-based answer, I normally start with Google scholar.com and will share with you some of my findings

Some estimates show that every cell in your body takes 10,000 oxidative hits to its DNA daily

(2019) 8:e1291

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If your dark spots have been hanging around for months and nothing seems to be shifting them, this Glutathione serum is worth trying