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To report suspected adverse reactions to Contrave, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

This effect appears to be direct and due to the binding of GIP to its receptor (GIPR) on the alpha cell surface ( 3.3 Ghrelin The gastrointestinal peptides that act on glucagon secretion also include ghrelin, a 28-amino-acid peptide primarily produced by X/A-like cells in the oxyntic glands of the gastric fundus

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Bea S, et al

These changes translate into higher chemical or clinical pregnancy rates in some studies but not in others

It has now also received FDA approval as a weight loss solution for those dealing with obesity