PE131020: β-GalNAc-PEG3-DBCO Pack Size:5 mg 5 / A β-D-lactose ligand

5 / A β-D-lactose ligand equipped with a terminal alkyne through a hydrophilic PEG3 spacer

C25H24D4N6O / 432

enabling sensitive

C63H99D8N11O29 / 1490

C45H55N3O20 / 957

PE131020: β-GalNAc-PEG3-DBCO Pack Size:5 mg 5 / A β-D-lactose ligandC33H41N3O10 639. 69 A D N acetylgalactosamine (GalNAc) ligand equipped with a dibenzocyclooctyne (DBCO) handle through a hydrophilic PEG3 spacer. The DBCO group reacts with azides via copper free strain promoted azide alkyne cycloaddition (SPAAC), forming stable 1,2,3 triazole linkages without a copper catalyst. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor