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The FDA label recommends using a non-oral contraceptive method or adding a barrier method for 4 weeks after starting tirzepatide and after each dose increase

Mano et al., 2013)

At the time, the FDA presented a lot of adverse event data that showed there was a risk of immunogenicity immune reactions and that raised some red flags for the committee, said Gupta, an adjunct assistant professor of anesthesiology at the Johns Hopkins University School of Medicine

Adequate protein intake is the single most important preventive measure

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