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doi:10.3109/08923973.2014.956752

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412 Minihepcidins, which are hepcidin agonists, improve anemia and iron overload in young -thalassemia model Hbb th3/+ mice, and enhance erythropoiesis without altering the beneficial effect of the iron chelating agent DFO on iron overload in older -thalassemia mice

4 Haem-iron is an important mediator of NTHi pathogenesis and persistence The success of NTHi as a pathogen is reliant on its ability to perform interactions with the host, many of which are regulated directly or indirectly by the bioavailability of haem or other iron-containing moieties (Harrison et al., 2013)

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