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Initially conceptualized as a therapeutic for neurodegenerative disorders such as Alzheimers and Parkinsons disease, its primary mechanism of action involves high-affinity binding to hepatocyte growth factor (HGF) and its cognate receptor c-Met

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Both Dihexa and wortmannin were prepared by dissolving the compounds in 10% DMSA, 40% PEG 300, 5% Tween 80, and 45% saline

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