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The resulting peptide fragments are all below 10 kilodaltons, allowing them to cross the blood-brain barrier and exert neurotrophic effects directly in the brain

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FIGURE 6 FIGURE 7 Glutathione Peroxidase 1 Inhibits the NF-B Pathway to Protect Against Peroxynitrite-Induced Spiral Ganglion Neurons Damage The transcription factor NF-B plays a vital role in cellular death and survival under oxidative stress conditions (Schneider et al., 1999

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