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The Bottom Line While severe constipation can create chest discomfort through diaphragmatic pressure, any chest pain warrants careful evaluation to rule out cardiac causes

The Downside of SLS in Toothpaste July 06, 2026 Many toothpastes contain the detergent SLS (sodium lauryl sulfate) but it can cause side effects in the mouth and possibly the esophagus

If constipation lasts more than a week, is accompanied by severe pain, blood in the stool, or unexplained weight loss, consult a healthcare provider promptly

02 Dissolve gently Gently swirl until dissolved

Here is how the four areas compare: Lower abdomen

Potential evening downsides The biggest risk with evening dosing is forgetting