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Drug-Specific Insights: The GIPR variants association with nausea and vomiting was restricted specifically to patients taking tirzepatide (which targets both GLP-1 and GIP receptors)

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Columbus Instruments, Columbus, OH, USA)

veterans with type 2 diabetes, the WashU Medicine team found GLP-1s are tied to a reduced risk of developing substance use disorders across all major addictive substances and to a reduced risk of severe harm, including overdose and death, in people who already have such disorders