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Melanotan 2 selectively binds to the melanocortin receptor MC1R, which regulates the conversion of tyrosine into eumelanina brown-to-black pigment that effectively absorbs UV rays and disperses them in the skins surface layers, actively protecting epidermal cells from oxidative stress

There are many agents with a well known depigmenting effect like pycnogenol, orchid extract, marine algae extract, cinnamic acid, soy, aloesin, Boswellia , hydroquinone, glycolic acid, arbutin, kojic acid, ascorbate, tocopherol, niacinamide, etc

A specific cautionary note is warranted here: if sulfuric acid is used instead of hydrochloric acid for cation resin regeneration, a step-wise introduction method must be strictly employed

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2000 Oct 24;39(42):13005-11

Foods that promote bowel regularity Prunes remain the evidence champion for constipation