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MIM is highly expressed in neuronal cells, kidney cells, immune cells, and endothelial cells 71,72,73,74,75 , suggesting that these tissues serve as natural sources of Rac1-containing EVs in circulation

results in disturbances in the homeostatic redox state of cells

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All the variables are scaled relative to their values at day 1

FDAs July 2026 briefing document states that the agency did not intend to issue a final determination until it considered committee input and completed its reviews

To compare cocultures versus monocultures, filtered datasets of each were combined and filtered using a P -value cutoff of 0.01