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It was initially discovered to bind to actin, which is part of the cytoskeleton, and influence cell migration for wound healing.[ref] Thymosin beta 4 was initially isolated from the thymus in calves, which is why it was named thymosin

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The enzyme is also a component of H2S signaling in cells

Due to its therapeutic potential, autophagy modulation attracts a great deal of interest from both academic and pharmaceutical institutions

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