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This cohort comprised a higher male-to-female sex ratio than the general population and further analysis based on sex and assessment of generalisability was not performed because of the small sample size
Per FDA guidance, GLP-1-based medications are generally approved for adults with a BMI over 30, or over 27 with a qualifying health condition such as type 2 diabetes, high blood pressure, or high cholesterol
doi: 10.1002/jat.2962, 208
Among these systems, glutathione (GSH) peroxidase 4 (GPX4) plays a dominant role by converting LOOH into nontoxic lipid alcohols (LOH) using GSH as an electron donor 10
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Clinical research has focused on its applications for reducing visceral fat and improving body composition in specific research populations, including studies on HIV associated lipodystrophy
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