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Physangulidethe first natural 22S-withasteroid

doi: 10.1016/s0022-5347(17)35291-6

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354 Ammonium is mainly produced in the gut by amino acid deamination with subsequent conversion to ammonium by urease containing bacteria and is detoxified in the liver by the urea cycle enzymes and by glutamine synthetase, highly expressed in hepatocytes