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In sensible cosmetic concentrations this is not a general concern, but it argues against casual escalation of dose or concentration in the belief that more is better

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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis

10.3892/ijo.2024.5658 146 ZhangL.SunW.GaoW.ZhangY.ZhangP.LiuY.et al (2024)

Seifi HS, Shelp BJ (2019) Spermine differentially refines plant defense responses against biotic and abiotic stresses

[3] Wang HaiLi,Zhang Jun,Li YuPing,Dong Lun,Chen YingZhu