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Hgb 9.8 g/dL (down from 11.2 six months ago), ferritin 11 ng/mL, TSAT 9%

Due to the increase of the senior population in recent years, age-related diseases such as neurodegenerative diseases have become more common and pose a serious threat to human health (World Health Organization, 2020)

Based on the OGTT, rats with similar glucose tolerance profile were paired, then these rats were randomized into treatment groups ( Figure S2 )

NaHCO 3 : Not recommended except if there is refractory acidosis, weak recommendation, low quality evidence (2C)

Krassas GE, Kaltsas TT, Pontikides N, Jacobs H, Blum W, Messinis I