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These intermediates can sometimes be more reactive than the original compounds

Open Biol 10:200004 Yang B-B, Lum PK, Hayashi MM, Roskos LK (2004) Polyethylene glycol modification of filgrastim results in decreased renal clearance of the protein in rats

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What is their adverse event reporting process

We hope that PEPlife will be a useful resource for researchers working in the area of designing of therapeutic peptides