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PMID 31559190

Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism

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Yet many patients often discontinue these medications due to gastrointestinal side effects such as nausea and diarrhea, loss of lean muscle mass, the need for injections, or high costs

Thanks to the access to two parallels flow channels, the device allowed the quantification of the intestinal barrier function, as well as the measurement of the transepithelial absorption and transport