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The reference method to assess IAH is the hyperinsulinaemichypoglycaemic clamp [115], although this is not used out of a research frame due to its invasiveness, cost and time commitment from people with diabetes
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29 GLP-1, an endocrine hormone, is secreted by enteroendocrine L-cells located in the distal jejunum, ileum, and colon in response to nutrient ingestion and neuroendocrine stimulation
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