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49 In another phase 1 study conducted in 37 Japanese patients, the most common treatment-related side effects were nausea, vomiting, abdominal discomfort, diarrhea, and headache, mostly mild to moderate in severity

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For example, a clinical trial involving semaglutide reported that participants with a baseline body mass index (BMI) over 35 kg/m lost an average of 15% of their body weight after 68 weeks, while those with lower baseline weights lost less in relative terms

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