Miquelianin-rich lotus leaf extract (LLE) significantly increases the expression of 3-adrenergic receptor (3-AR) and p-AMP-activated protein kinase (AMPK)/AMPK ratio in the inguinal white adipose tissues of in vitro models established by the differentiation of 3T3-L1 cells and in high-fat diet-induced obese mice, thus significantly decreasing the protein expression of the mitophagy markers, PINK1, Parkin, Beclin1 and LC3B, up-regulating the expressions of p62 and Drp1, increasing the expression of beige fat-enriched marker proteins nuclear respiratory factor 1 (Nrf1), mitochondrial transcription factor A (TFAM), PPAR, and cytochrome oxidase subunit VII a (Cox7a), and upregulated the protein levels of mitochondrial biogenesis markers, silent information regulator 1 (SIRT1), peroxisome proliferator-activated receptor coactivator 1 (PGC-1), uncoupling protein 1 (UCP1) and fibroblast growth factor 21 (FGF21) levels
During the procedure, your doctor will make a small incision in your shoulder
When investigating elevated B12, additional tests such as active B12 (holotranscobalamin), methylmalonic acid, and homocysteine may help clarify true B12 status
Visceral fat is linked to metabolic disorders, inflammation, and increased cardiovascular risk (12)
This product is supplied in an arginine salt form to support stability and handling characteristics relevant to laboratory research environments
Research Applications and Domains Cellular and Tissue Studies The bulk of BPC-157 research relevant to muscle recovery comes from cellular and tissue-based animal models
