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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice (in Eng)

doi: 10.2337/diacare.28.5.1083

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NNMT-related research is relevant to models involving adipocyte biology, NAD+-associated pathways, methylation-linked metabolism, and cellular energy regulation

Optimizing foundational factors reduces side effect risk

Some patients also experience mild diarrhea, swelling, or itching