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ROS can initiate different modes of cell death through their oxidative effects on specific redox-sensitive proteins

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Another study revealed that the oral administration of Polygonum cuspidatum aqueous extract in rats with resected exorbital lacrimal glands restored tear volume and Mucin4 (MUC4) expression by mitigating corneal abnormality and the release of inflammatory cytokines [76]

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Selank inhibits the enzymes that break down enkephalins, which are ligands for opioid receptors