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Important things to consider for the rate of administration include: Watching the patients vital signs Changing the rate based on how the patient reacts Not giving it too fast to prevent bad reactions Emergency Protocols for Severe Deficiency For severe Vitamin B12 deficiency with neurological symptoms or severe anemia, emergency steps are needed

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Am J Physiol - Hear Circ Physiol

Zhong, Nanosuspension drug delivery system: preparation, characterization, postproduction processing, dosage form, and application, in Nanostructures for Drug Delivery, Elsevier, 2017, pp

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