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Gene expression profiling reveals a signaling role of glutathione in redox regulation
They are often used to reduce the risk of heart attack, stroke or clotting after certain heart procedures
In the absence of the cluster, such monothiol glutaredoxins can still be glutathionylated 26,27,29 and might (slowly) transfer the glutathione moiety to reduced cysteine residues as suggested for the AtGrxS15-dependent oxidation of reduced roGFP2 by GSSG
