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GRK2 overexpression can also regulate the signal transduction ability of EGFR in promoting the activation of extracellular regulated protein kinase (ERK)/MAPK via phosphorylation (26)

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Starting with the upregulation of 7nAChR, which is considered the key factor of the mechanism, results in the downregulation of brain injury markers, including NF-B and Bax, produced anti-inflammatory and antiapoptotic effects on the brain of autistic animals [62]