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Neuroprotective effects of thymosin 4 after traumatic brain injury in rats. J Neurosurg 2012

As monotherapy, cagrilintide produced 11.8% weight loss in the Phase 3 REDEFINE 1 trial at 68 weeks with the 2.4 mg dose

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The authors note that GHSs likely behave as functional somatostatin antagonists while enhancing GHRH-secreting neurons, that their GH-releasing effect is independent of gender but undergoes marked age-related variation, and that their activity is not fully specific for GH: they also produce slight prolactin release and, in Cushing disease, ACTH and cortisol responses

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Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways