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Each occupies a different therapeutic question, but the rigour applied to evaluating them (mechanism, dose-response, safety, certificate of analysis) is the same

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Holland, N

High levels of cortisol can impair memory retrieval, disrupt focus, and inhibit creative problem-solving

But here are some general guidelines: Severe deficiencies: Daily shots for 1 week, then weekly shots until levels normalize Moderate deficiencies: Weekly shots until the deficiency is corrected Maintenance dosing : Monthly shots to keep B12 levels optimal Its definitely possible to take B12 shots too often