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This makes it a topic that requires a balanced, clinical perspective

FDA pharmacovigilance review of FAERS reports for compounded GLP-1s has documented dosing errors, inadvertent overdoses, and product quality concerns linked specifically to the regulatory gap between compounded and brand-name product (Hoffman et al., 2025)

We hypothesize that semaglutides cognitive benefits are at least partially independent of weight loss, although concurrent metabolic improvements make it difficult to disentangle direct effects from secondary ones