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The study demonstrated for the first time that the C718T polymorphism in the 3-untranslated region of the GPX4 gene could be considered as a genetic marker of susceptibility to CS in patients with EH

Moreover, inflammatory mediators, such as Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) and Tumor necrosis factor-alpha (TNF-) increased, while pivotal proteins involved in dendritic and synaptic development, such as Synaptophysin (SYP), postsynaptic density protein 95 (PSD95) and brain-derived neurotrophic factor (BDNF) decreased in APP/PS1 mice

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No visible results Some users see dramatic results

doi:10.1016/j.neulet.2022.136620 16

Bridging butyrate and protein post-translational modification Studies have extensively investigated how butyrate mediates physiological effects by activating GPCRs and inhibiting HDACs