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Pain management may need review as you lose weight, since weight loss often reduces musculoskeletal pain

Some patients notice a peak in side effects, including the chills, shortly after their dose as the medication concentration in the blood is at its highest

Also, these drugs are already showing very serious side effects and yet they are being aggressively pushed on fat people, including by Novo Nordisk which, again, has promised massive sales to their shareholders

PubMed Dhaliwal S, et al

Biomarker Context: When Dual Therapy May Be Most Relevant Individual response to combination therapy correlates with baseline metabolic phenotype