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Furthermore, reduced glutathione can also mitigate the oxidative stress produced by enzymes in phase I detoxification in the liver

Kidney markers, bicarbonate and oxidative stress should be interpreted alongside it

In some protocols using hMECs, cells were pre-incubated with MLN-4760 (440 pM) (5306160001, MilliporeSigma) or diminazine aceturate (DIZE

Mechanistically, they activate Nrf2 and block ubiquitin-mediated GPX4 degradation, thereby inhibiting ferroptosis and alleviating cartilage erosion, pain, and gait abnormalities in DMM-induced OA (192)

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