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Outside narrow, documented medical need, compounded versions of these drugs are no longer a lawful option, and FDA has logged hundreds of adverse event reports, some requiring hospitalization, tied to dosing errors from patients measuring their own doses out of compounded vials

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Here, well delve into the intricacies of maintaining GLP-1 medications, set expectations on how long patients should stay on GLP-1 medications, and offer insights into the best practices for patients looking to stop their GLP-1 journey

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doi: 10.1038/nrendo.2015.7 30 SudoSSudoMSimonsCTDessirierJMCarstensE

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Electrophysiological recordings support this notion and have demonstrated that GLP-1 directly stimulates POMC/CART cells, whereas GLP-1 can also inhibit orexigenic NPY/AgRP cells in the ARC through an indirect mechanism (Secher et al., 2014)

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