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HMSC pretreated with Ex-4 or modified to express Exendin-4 (hMSC-Ex-4) showed reduced HO-induced apoptosis and increased phosphorylated AMPK levels, effects blocked by the AMPK inhibitor compound C [18]

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Relative to their blood glucose levels at time 0, the GLP-1RA group exhibited a slightly elevated ITT response compared to the DB group (Fig