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Plant oils like canola, walnut, olive, flaxseed, and coconut oil have anti-inflammatory effects due to bioactive compounds such as omega-3 fatty acids and polyphenols, which inhibit pro-inflammatory mediators like prostaglandins, cytokines (eg, tumor necrosis factor [TNF]-, interleukin [IL]-6), and NF-B signaling pathways

J Am Coll Nutr 37:387398

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It promotes mucosal immunity by increasing IgA (+) cells and reducing pro-inflammatory cytokines (IL-1, IL-6, TNF-), while enhancing beneficial bacterial genera such as Romboutsia (Brasiel et al., 2025

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells