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In canonical Wnt/-catenin signaling, the secreted Wnt ligands bind with the Frizzled receptor, which further inactivates glycogen synthase kinase-3 (GSK-3), which is an enzyme responsible for the ubiquitination-mediated degradation of -catenin 4,5

Suppressing IGF1R reduces DNA damage repair by decreasing ATM phosphorylation, which played a critical role in HR and NHEJ (Turney et al., 2012

Among its bioactive constituents, the monomeric lignan anwuligan has been identified to possess notable anti-apoptotic, antioxidant, and anti-inflammatory properties (Zhang et al., 2019

Hyaluronic Acid and Elastin Hydrolyzate work together to enhance skin moisture retention and elasticity

In this episode of The Human Upgrade, Host Dave Asprey explores one of the most underrated molecules in functional medicine and biohacking: glutathione